4LIFE TRANSFER FACTOR®
Mammalian transfer factors, including those of humans are small molecules between 3,500 and 10,000 daltons. (1; 2) Transfer factors are polypeptides that consist of 40 to 44 amino acids (3) and have a conserved region and a variable region. From a molecular biological standpoint, these two properties are analogous to antibodies; however transfer factor's functions of cell mediated immunity (CMI) and non-specific immunological activity differ almost completely from the functions of antibodies. The molecules that have a molecular weight of less than 3,500 daltons modulate immune response but they do not transfer delayed-type hypersensitivity (DTH). (1)
Transfer factors were first discovered in 1949 by H. Sherwood Lawrence when he demonstrated that CMI could be transferred from one individual to another by way of low molecular weight extracts of white blood cells. Transfer factors could transfer DTH of a specific form from a skin test positive individual to a skin test negative individual who subsequent to the transfer would skin test positive for that antigen. (6) In a subsequent study in 1955 he demonstrated that DTH could be passed serially, first from a skin test positive individual to a test negative individual, who became test positive, then 6 months later from the second individual to another test negative individual who became test positive. (7) At the time antibodies were the focus of immune research and little was known of the importance of DTH and of the involvement of T-cells in immune response. Transfer factors promote wellness via cell mediated immunity. These compounds are components of colostrum, an infant's first meal. They bridge the generational gap by passing cell mediated immunity from mother to infant.
CLINICAL AND EXPERIMENTAL STUDIES
Natural Killer Cell Activity
CD4 T Helper Cell Research
Salivary Secretory IgA-Preliminary Investigation
4Life® Transfer Factor Plus® Tri-Factor® Formula
4Life Transfer Factor® RioVida® Tri-Factor® Formula
4Life Transfer Factor Renuvo®
4Life Transfer Factor® Chewable Tri-Factor® Formula
4Life Transfer Factor® Classic
4Life Transfer Factor® Immune Spray
4Life Transfer Factor® KBU®
4Life Transfer Factor® Belle Vie®
4Life Transfer Factor® Cardio
4Life Transfer Factor® GluCoach®
4Life Transfer Factor® MalePro®
4Life Transfer Factor® ReCall®
4Life Transfer Factor Reflexion™
4Life Transfer Factor Vista®
RiteStart® Kids & Teens
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- Kabirov, K.K. 2009, unpublished: University of Illinois at Chicago.
- Burbano, Z. and G. Sarmiento . 2013. Facultad de Ciencias Quimicas, Universidad de Guayaquil, Ecuador.